Disease: Axonal neuropathy
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TRPV4 Q9HBA0 transient receptor potential cation channel subfamily V member 4 Ion channel 2.2E-16 0.457 0.808
TRIM2 Q9C040 tripartite motif containing 2 Enzyme 1.00 0.686 0.538
TDP1 Q9NUW8 tyrosyl-DNA phosphodiesterase 1 Enzyme 1.3E-17 0.612 0.538
SPG11 Q96JI7 SPG11 vesicle trafficking associated, spatacsin 1.6E-39 0.576 0.538
SETX Q7Z333 senataxin Enzyme 0.95 0.570 0.731
RAB7A P51149 RAB7A, member RAS oncogene family 0.97 0.597 0.692
POLG P54098 DNA polymerase gamma, catalytic subunit Enzyme 2.1E-09 0.457 0.846
PNKP Q96T60 polynucleotide kinase 3'-phosphatase 3.7E-14 0.553 0.692
PMP22 Q01453 peripheral myelin protein 22 Cellular structure 0.91 0.471 0.885
PLP1 P60201 proteolipid protein 1 Cellular structure 0.93 0.543 0.769
PDK3 Q15120 pyruvate dehydrogenase kinase 3 Kinase 0.45 0.678 0.500
NEFL P07196 neurofilament light 0.488 0.769
MTMR2 Q13614 myotubularin related protein 2 Enzyme 3.0E-07 0.659 0.538
MPZ P25189 myelin protein zero 0.27 0.503 0.846
MPV17 P39210 mitochondrial inner membrane protein MPV17 Receptor 9.7E-11 0.595 0.577
MFN2 O95140 mitofusin 2 Enzyme 0.99 0.471 0.846
LMNA P02545 lamin A/C 1.00 0.384 0.885
KIF5A Q12840 kinesin family member 5A Cellular structure 1.00 0.593 0.731
KIF1B O60333 kinesin family member 1B Cellular structure 1.00 0.516 0.808
HSPB8 Q9UJY1 heat shock protein family B (small) member 8 4.3E-02 0.570 0.577
HSPB1 P04792 heat shock protein family B (small) member 1 2.8E-07 0.436 0.808
HINT1 P49773 histidine triad nucleotide binding protein 1 Enzyme 1.8E-03 0.619 0.577
GJB1 P08034 gap junction protein beta 1 Cell-cell junction 0.85 0.514 0.731
GDAP1 Q8TB36 ganglioside induced differentiation associated protein 1 3.2E-08 0.612 0.538
GARS1 P41250 glycyl-tRNA synthetase 1 Enzyme 0.31 0.623 0.500